o hui

The First Geniture Ampoule Advanced

O Hui - The First Geniture Ampoule Advanced

Product overview

Brand: O Hui
Product Name: The First Geniture Ampoule Advanced
Korean Product Name: 더 퍼스트 제너츄어 앰풀 어드밴스드
Capacity: 40ml
Formulated by: LG Household & Health Care
Manufactured by: LG Household & Health Care
Distributed by: LG Household & Health Care
Country of Manufacture: South Korea
Functional Cosmetic Certifications: n/a
Original Retail Price: 355,000 KRW
Date of Release: May 2024
Shelf life: 3 years before opening. 12 months after opening.

Ingredients


Notable allergens: Alcohol, Essential Oils, Fragrance, Mica, Niacinamide.

Water, Glyceryl Polymethacrylate, Glycerin, Dipropylene Glycol, Alcohol Denat., Butylene Glycol, 1,2-Hexanediol, Propylene Glycol, Niacinamide, Isopentyldiol, Panthenol, Dimethicone, Polymethylsilsesquioxane, Alanyl Glutamine, Propanediol, Dunaliella Salina Extract, Sodium Polyacryloyldimethyl Taurate, Macrocystis Pyrifera (Kelp) Extract, PEG-60 Hydrogenated Castor Oil, Lauryl Dimethicone/Polyglycerin-3 Crosspolymer, Alcohol, Myristica Fragrans (Nutmeg) Extract, PEG-8 Caprylic/Capric Glycerides, Carbomer, Dipotassium Glycyrrhizate, Polyacrylate Crosspolymer-6, Tromethamine, Hydroxyethylcellulose, Fragrance, Sodium Polyacrylate, Trisodium EDTA, Mica, Rhus Semialata Extract, Titanium Dioxide (CI 77891), Hydrogenated Lecithin, Dimethicone/Vinyl Dimethicone Crosspolymer, Pentylene Glycol, Sodium Hyaluronate, Eclipta Prostrata Extract, Amodimethicone, Disodium EDTA, Sodium Hydroxide, Trehalose, Iron Oxide Red, Polysorbate 20, Ethylhexylglycerin, Sodium Chloride, Sodium Bicarbonate, Disodium Adenosine Triphosphate*, Myrtus Communis Extract, Gold, Sodium Lactate, Glucose, Sodium Phosphate, Disodium Phosphate, Glycoproteins**, Potassium Chloride, Glycine, Cyanocobalamin*, Thioctic Acid, Glycyrrhetinic Acid, Lysine HCl, Sodium Pyruvate, Isoleucine, Leucine, Tyrosine, Threonine, Valine, Arginine HCl, Phenylalanine, Cystine, Calcium Chloride, Histidine HCl, Serine, Methionine, Paeonia Suffruticosa Branch/Flower/Leaf Extract, Palmitoyl Tripeptide-1, Tryptophan, Palmitoyl Tetrapeptide-7, Inositol, Folic Acid, Pyridoxine HCl, Thiamine HCl, Copper Tripeptide-1, Riboflavin, Limonene, Citronellol, Linalool, Benzyl Salicylate, Geraniol

*Signature Cell 83™
**Transkin™

정제수, 글리세릴폴리메타크릴레이트, 글리세린, 다이프로필렌글라이콜, 변성알코올, 부틸렌글라이콜, 1,2-헥산다이올, 프로필렌글라이콜, 나이아신아마이드, 아이소펜틸다이올, 판테놀, 다이메티콘, 폴리메틸실세스퀴옥세인, 알라닐글루타민, 프로판다이올, 두날리엘라 살리나추출물, 소듐폴리아크릴로일다이메틸타우레이트, 자이언트켈프추출물, 피이지-60하이드로제네이티드캐스터오일, 라우릴다이메티콘/폴리글리세린-3크로스폴리머, 에탄올, 육두구추출물, 피이지-8카프릴릭/카프릭글리세라이즈, 카보머, 다이포타슘글리시리제이트, 폴리아크릴레이트크로스폴리머-6, 트로메타민, 하이드록시에틸셀룰로오스, 향료, 소듐폴리아크릴레이트, 트라이소듐이디티에이, 마이카, 붉나무추출물, 티타늄디옥사이드 (CI 77891), 하이드로제네이티드레시틴, 다이메티콘/비닐다이메티콘크로스폴리머, 펜틸렌글라이콜, 소듐하이알루로네이트, 한련초추출물, 아모다이메티콘, 다이소듐이디티에이, 소듐하이드록사이드, 트레할로오스, 적색산화철, 폴리솔베이트20, 에틸헥실글리세린, 소듐클로라이드, 소듐바이카보네이트, 다이소듐아데노신트라이포스페이트*, 마텔추출물, 금, 소듐락테이트, 글루코오스, 소듐포스페이트, 다이소듐포스페이트, 글라이코프로테인**, 포타슘클로라이드, 글라이신, 사이아노코발아민*, 티옥틱애씨드, 글리시레티닉애씨드, 라이신에이치씨엘, 소듐파이루베이트, 아이소류신, 류신, 타이로신, 트레오닌, 발린, 알지닌에이치씨엘, 페닐알라닌, 시스틴, 칼슘클로라이드, 히스티딘에이치씨엘, 세린, 메티오닌, 모란가지/꽃/잎추출물, 팔미토일트라이펩타이드-1, 트립토판, 팔미토일테트라펩타이드-7, 이노시톨, 폴릭애씨드, 피리독신에이치씨엘, 티아민에이치씨엘, 카퍼트라이펩타이드-1, 리보플라빈, 리모넨, 시트로넬올, 리날룰, 벤질살리실레이트, 제라니올

*시그니처83셀™
**트랜스킨™

Product description

O Hui’s “The First Geniture Ampoule Advanced” is a prestige skin-illuminating ampoule that contains twice the concentration of Signature 83 Cell™1, the key ingredient of “The First Geniture” line, to elevate the skin’s vitality, radiance, and moisture. The product is formulated with precious gold to give the skin a refined golden radiance.

O Hui’s “The First Geniture Ampoule Advanced” features a nourishing and deeply hydrating texture that helps replenish skin elasticity and reinforce the skin’s natural protective barrier, resulting in a sophisticated radiance that gleams gracefully, even in the dark.

[1] The concentration of Signature 83 Cell™ is double compared to the one of O Hui’s “The First Geniture Skin Softener”.

O Hui’s “The First Geniture”: a crescendo of skin radiance

A radiance that emerges from deep within the skin, becoming increasingly brilliant with each passing moment: “The First Geniture”’s crescendo of skin radiance. O Hui’s “The First Geniture”, the ultimate skin radiance solution that has been perfected over five generations across eighteen years, is now more powerful than ever.

Through the analysis of 60,000 genetic datasets and AI-based screening across 830,000 candidate active ingredients, O Hui identified Signature Cell 83™, a one-of-a-kind skin illuminating ingredient born from the convergence of science and technology.

A triple crescendo of skin radiance

At the heart of the new O Hui’s “The First Geniture” line is the Signature Cell 83™2 complex, an exclusive ingredient that helps support 83 biological indicators of skin vitality. The ingredient is designed to improve skin firmness, refine texture, and boost radiance, resulting in a crescendo of skin radiance.

[2] Signature Cell 83™ represents an upgraded skin-illuminating ingredient compared to the previous Signature 29 Cell™ complex, which supported 9 biological indicators of skin vitality.

The line delivers a triple crescendo of skin radiance that grows stronger from deep within the skin. Clinical testing for O Hui’s “The First Geniture” line showed:

  • Visible improvement in skin firmness after 7 days of use3.
  • Refinement of texture after 14 days of use3.
  • Enhanced skin radiance after 28 days of use3.

[3] Tests conducted by: Korea Institute of Dermatological Sciences.
Participants: 31 women aged 25-67
Date: 28 December 2023 – 25 January 2024.
Test protocol: Participants applied O Hui’s “The First Geniture Softener” as directed.

Point 1: Signature Cell 83™

O Hui’s “The First Geniture” line is formulated with Signature Cell 83™, a one-of-a-kind ingredient. The ingredient consists of:

  • ATP, a skin-firming ingredient that helps support skin elasticity and vitality.
  • Cyanocobalamin, a skin-illuminating ingredient that helps promote a clear and radiant complexion.

Point 2: Advanced technology

O Hui’s “The First Geniture” line is powered by LG’s proprietary patented ingredients to help deliver a clearer, firmer, more radiant complexion.

  • Trehalose. The line is formulated with Trehalose to help increase hydration in the stratum corneum, allowing light to pass through the skin more effectively (“skin optimal clearing”). This technology is protected by the registered patent for stratum corneum clarification, No. 10-2015903.
  • Tension Complex. The line is formulated with Tension Complex to firm the skin’s elastic layer, allowing skin to reflect light more effectively.
O Hui - The First Geniture Skin Softener

O Hui’s “The First Geniture” line is formulated with Transkin™, a patented delivery technology registered in six countries4, which is designed to improve the absorption of active ingredients into the skin.

[4] Transkin™ is patented in Korea (KR 10-1329411), the United States (US 9687560), China (CN 104640558), Japan (JP 5963953), Europe (EP 2857033), and Hong Kong (HK 12134070).

O Hui’s “The First Geniture Ampoule Advanced”

O Hui’s “The First Geniture Ampoule Advanced” delivers a sophisticated radiance that gleams gracefully, even in the dark. With a formula infused with precious gold, O Hui’s “The First Geniture Ampoule Advanced” is a prestige skin-illuminating ampoule that helps enhance skin vitality, lustre and moisture to reveal a radiant, luminous complexion.

Point 1: A radiant glow that stands out even in the dark

O Hui’s “The First Geniture Ampoule Advanced” gives skin a radiant glow that stands out even in the dark.

  • The product has been shown to increase skin radiance by 4.96 times immediately after a single application5.

[5] Evaluation of the product’s efficacy in improving skin radiance under low-light conditions in comparison to untreated areas (please note that the effect is only temporary).
Tests conducted by: Ellead Co., Ltd.
Participants: 33 women aged 24–60 years.
Date: 10 January – 8 February 2024.

Point 2: Prestige skin-illuminating ampoule

O Hui’s “The First Geniture Ampoule Advanced” is a prestige skin-illuminating ampoule that leaves the skin brimming with vitality.

Improvement in skin density:
  • The product has been shown to enhance skin density by 5.04% after two weeks of use6.
  • The product has been shown to enhance skin density by 9.45% after four weeks of use6.
O Hui - The First Geniture Ampoule Advanced

[6] Tests conducted by: Ellead Co., Ltd.
Participants: 33 women aged 24–60 years.
Date: 10 January – 8 February 2024.

Improvement in skin barrier function:
  • The product has been shown to improve skin barrier function by 75.76% after just one day of use7.
O Hui - The First Geniture Ampoule Advanced

[7] Tests conducted by: Ellead Co., Ltd.
Participants: 30 women aged 24–58 years.
Date: 10-12 January 2024.

Skin soothing effect:
  • The product has been shown to alleviate skin irritation by 6.7 times after one day of use8.
O Hui - The First Geniture Ampoule Advanced

[8] Tests conducted by: Ellead Co., Ltd.
Participants: 30 women aged 24–58 years.
Date: 10-12 January 2024.

Point 3: Double the concentration9 of Signature 83 Cell™

O Hui’s “The First Geniture Ampoule Advanced” features double the concentration9 of Signature 83 Cell™, the key ingredient in “The First Geniture” line. The ampoule is formulated with a more potent concentration of Signature 83 Cell™, the key ingredient in “The First Geniture” line, to make skin healthy and brimming with vitality.

[9] The concentration of Signature 83 Cell™ is double compared to the one of O Hui’s “The First Geniture Skin Softener”.

Point 4: Texture

O Hui’s “The First Geniture Ampoule Advanced” boasts a luxurious texture that blends seamlessly into the skin, leaving it firm and moisturised all at once. Its dense texture infused with gold melts seamlessly into the skin upon application, providing deep nourishment and intense moisture.

How to use

Here are two tips to apply O Hui’s “The First Geniture Ampoule Advanced”:

  • STEP 1: After applying “The First Geniture Cell Essential Source”, and before using your essence or serum, apply “The First Geniture Ampoule Advanced” on your face and neck.
  • STEP 2: Softly press your palms over the entire face to promote better absorption. For areas that need more quicker improvement, apply an additional layer for better results.

Directions

Take the desired amount of product and spread it evenly across the face to ensure optimal absorption. For areas requiring more intensive care, apply an additional layer for better results.

Precautions

  1. General precautions:
    • Immediately consult a dermatologist if symptoms such as red blotches, swelling and/or itchiness appear while using the product, or in case such symptoms appear when the skin is exposed to direct sunlight after use.
    • Do not use the product on open wounds.
    • Storage and handling precautions:
      • Keep out of the reach of children.
      • Keep away from direct sunlight.

Other editions and formulations

Previous formulations:

  • The First Geniture Ampoule Advanced [launched: March 2018, formulated and manufactured by: LG Household & Health Care]
  • The First Ampoule Advanced [launched: August 2016, formulated and manufactured by: LG Household & Health Care]
  • The First Cell Revolution Ampoule [launched: August 2013, formulated and manufactured by: LG Household & Health Care]
  • The First Cell Revolution Ampoule [launched: January 2010, formulated and manufactured by: LG Household & Health Care]
  • The First Cell Intensive Recovery [launched: January 2007, formulated and manufactured by: LG Household & Health Care]

Special editions:

  • The First Geniture Ampoule Advanced Crescendo Holiday Edition [limited edition 80ml jumbo size + 20ml set, launched: October 2024]
  • The First Geniture Ampoule Advanced Holiday Edition [limited edition 80ml jumbo size + 20ml set, launched: October 2025]
  • O Hui - The First Geniture Ampoule Advanced Crescendo Holiday Edition 2024
    O Hui – The First Geniture Ampoule Advanced Crescendo Holiday Edition 2024
  • O Hui - The First Geniture Ampoule Advanced Holiday Edition 2025
    O Hui – The First Geniture Ampoule Advanced Holiday Edition 2025

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    Review

    n/a

    Source: O Hui official website and official product packaging
    Translation: © 2025 Odile Monod. You may not reproduce the above translation for commercial purposes without the express written consent of the translator.

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    Odile Monod is a Korea-based art director with an extensive background in the beauty industry, having worked for internationally renowned conglomerates across Europe and Asia. Her long-standing passion for Korean beauty led her to create The Monodist, a platform where she shares her expertise and industry knowledge with those who want to better understand and navigate the complex world of K-Beauty.

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